Human (GRCh38.p14)
Description

DNA topoisomerase III alpha [Source:HGNC Symbol;Acc:HGNC:11992]

Gene Synonyms

TOP3, ZGRF7

Location
About this transcript

This transcript has 19 exons, is annotated with 37 domains and features, is associated with 20905 variant alleles and maps to 928 oligo probes.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000321105.10TOP3A-20165961001aaENSP00000321636.5
 
Protein coding
CCDS11194Q13472-1 NM_004618.5MANE SelectEnsembl CanonicalGENCODE basicAPPRIS P1TSL:1
ENST00000580095.5TOP3A-2082929976aaENSP00000462790.1
 
Protein coding
Q13472-2 -TSL:1CDS 3' incomplete
ENST00000489131.1TOP3A-20658225aaENSP00000465864.1
 
Protein coding
K7EL07 -TSL:3CDS 5' incomplete
ENST00000584582.5TOP3A-216366169aaENSP00000462136.1
 
Nonsense mediated decay
J3KRR9 -TSL:5
ENST00000582981.5TOP3A-213323989aaENSP00000462378.1
 
Nonsense mediated decay
J3KS96 -TSL:2
ENST00000461127.5TOP3A-202823139aaENSP00000464338.1
 
Nonsense mediated decay
J3QR18 -TSL:3
ENST00000581536.5TOP3A-210766163aaENSP00000466641.1
 
Nonsense mediated decay
K7EMT6 -TSL:5CDS 5' incomplete
ENST00000585031.2TOP3A-21957595aaENSP00000464493.1
 
Nonsense mediated decay
J3QS25 -TSL:4
ENST00000582122.1TOP3A-211553133aaENSP00000466099.1
 
Nonsense mediated decay
K7ELI7 -TSL:4CDS 5' incomplete
ENST00000493648.1TOP3A-20750352aaENSP00000465014.1
 
Nonsense mediated decay
K7EJ41 -TSL:2CDS 5' incomplete
ENST00000582230.5TOP3A-212588No protein-
 
Protein coding CDS not defined
--TSL:4
ENST00000584669.5TOP3A-217580No protein-
 
Protein coding CDS not defined
--TSL:4
ENST00000584887.1TOP3A-218545No protein-
 
Protein coding CDS not defined
--TSL:5
ENST00000469739.6TOP3A-2033196No protein-
 
Retained intron
--TSL:2
ENST00000583804.2TOP3A-2151465No protein-
 
Retained intron
--TSL:5
ENST00000472959.5TOP3A-204913No protein-
 
Retained intron
--TSL:3
ENST00000583328.5TOP3A-214727No protein-
 
Retained intron
--TSL:2
ENST00000477508.1TOP3A-205600No protein-
 
Retained intron
--TSL:2
ENST00000580713.1TOP3A-209474No protein-
 
Retained intron
--TSL:2
Statistics

Exons: 19, Coding exons: 19, Transcript length: 6,596 bps, Translation length: 1,001 residues

MANE

This MANE Select transcript contains ENSP00000321636 and matches to NM_004618.5 and NP_004609.1

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q13472

CCDS

This transcript is a member of the Human CCDS set: CCDS11194

Transcript Support Level (TSL)

TSL:1

Version

ENST00000321105.10

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.