Human (GRCh38.p14)
Description

lamin A/C [Source:HGNC Symbol;Acc:HGNC:6636]

Gene Synonyms

CMD1A, HGPS, LGMD1B, LMN1, LMNL1, MADA, PRO1

About this transcript

This transcript has 12 exons, is annotated with 76 domains and features, is associated with 12419 variant alleles and maps to 849 oligo probes.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000368300.9LMNA-2053178664aaENSP00000357283.4
 
Protein coding
CCDS1129P02545-1 NM_170707.4MANE SelectEnsembl CanonicalGENCODE basicAPPRIS P1TSL:1
ENST00000675667.1LMNA-2292826729aaENSP00000501803.1
 
Protein coding
A0A6Q8PFJ0 -GENCODE basic
ENST00000676385.2LMNA-2362811634aaENSP00000502091.1
 
Protein coding
P02545-3 -GENCODE basic
ENST00000504687.7LMNA-2192721478aaENSP00000426535.3
 
Protein coding
H0YAB0 -GENCODE basicTSL:4
ENST00000361308.9LMNA-2012465664aaENSP00000355292.6
 
Protein coding
CCDS1129P02545-1 -GENCODE basicAPPRIS P1TSL:5
ENST00000368301.6LMNA-2062461572aaENSP00000357284.2
 
Protein coding
CCDS1131P02545-2 -GENCODE basicTSL:2
ENST00000675939.1LMNA-2322401664aaENSP00000502256.1
 
Protein coding
CCDS1129P02545-1 -GENCODE basicAPPRIS P1
ENST00000683032.1LMNA-2402329664aaENSP00000506771.1
 
Protein coding
CCDS1129P02545-1 -GENCODE basicAPPRIS P1
ENST00000682650.1LMNA-2392288634aaENSP00000506904.1
 
Protein coding
P02545-3 -GENCODE basic
ENST00000368299.7LMNA-2042253614aaENSP00000357282.3
 
Protein coding
CCDS72941P02545-6 -GENCODE basicTSL:1
ENST00000677389.1LMNA-2382029572aaENSP00000503633.1
 
Protein coding
CCDS1131P02545-2 NM_005572.4MANE Plus ClinicalGENCODE basic
ENST00000473598.6LMNA-2122015565aaENSP00000421821.1
 
Protein coding
P02545-5 -GENCODE basicTSL:2
ENST00000448611.6LMNA-2071943574aaENSP00000395597.2
 
Protein coding
CCDS58038P02545-4 -GENCODE basicTSL:2
ENST00000368297.5LMNA-2021679491aaENSP00000357280.1
 
Protein coding
CCDS72942Q5TCI8 -GENCODE basicTSL:2
ENST00000675881.1LMNA-2313218342aaENSP00000501670.1
 
Nonsense mediated decay
A0A6Q8PF80 --
ENST00000676434.1LMNA-2373212342aaENSP00000501648.1
 
Nonsense mediated decay
A0A6Q8PF80 --
ENST00000684195.1LMNA-2423081540aaENSP00000508220.1
 
Nonsense mediated decay
A0A804HL68 --
ENST00000674720.1LMNA-2263016516aaENSP00000502798.1
 
Nonsense mediated decay
A0A6Q8PHQ9 --
ENST00000674600.1LMNA-2252576126aaENSP00000501666.1
 
Nonsense mediated decay
A0A6Q8PF59 --
ENST00000676208.1LMNA-2342528342aaENSP00000502468.1
 
Nonsense mediated decay
A0A6Q8PF80 --
ENST00000674518.1LMNA-2242391214aaENSP00000502261.1
 
Nonsense mediated decay
A0A6Q8PGH0 --
ENST00000675455.1LMNA-228229736aaENSP00000501795.1
 
Nonsense mediated decay
A0A6Q8PFF5 --
ENST00000675874.1LMNA-2302239123aaENSP00000501851.1
 
Nonsense mediated decay
A0A6Q8PFM1 --
ENST00000515459.5LMNA-22175738aaENSP00000424518.1
 
Nonsense mediated decay
D6RB20 -TSL:5
ENST00000469565.6LMNA-209591No protein-
 
Protein coding CDS not defined
--TSL:4
ENST00000502751.5LMNA-218570No protein-
 
Protein coding CDS not defined
--TSL:4
ENST00000515711.1LMNA-222569No protein-
 
Protein coding CDS not defined
--TSL:5
ENST00000470199.2LMNA-210551No protein-
 
Protein coding CDS not defined
--TSL:4
ENST00000502357.5LMNA-217537No protein-
 
Protein coding CDS not defined
--TSL:4
ENST00000470835.1LMNA-211472No protein-
 
Protein coding CDS not defined
--TSL:3
ENST00000495341.5LMNA-214394No protein-
 
Protein coding CDS not defined
--TSL:5
ENST00000683773.1LMNA-241288No protein-
 
Protein coding CDS not defined
---
ENST00000478063.2LMNA-213285No protein-
 
Protein coding CDS not defined
--TSL:5
ENST00000675989.1LMNA-2333616No protein-
 
Retained intron
---
ENST00000676283.1LMNA-2353342No protein-
 
Retained intron
---
ENST00000496738.6LMNA-2152987No protein-
 
Retained intron
--TSL:2
ENST00000675431.1LMNA-2271514No protein-
 
Retained intron
---
ENST00000368298.2LMNA-2031475No protein-
 
Retained intron
--TSL:1
ENST00000498722.3LMNA-2161031No protein-
 
Retained intron
--TSL:2
ENST00000459904.2LMNA-208919No protein-
 
Retained intron
--TSL:2
ENST00000506981.1LMNA-220576No protein-
 
Retained intron
--TSL:2
ENST00000515824.1LMNA-223393No protein-
 
Retained intron
--TSL:2
Statistics

Exons: 12, Coding exons: 12, Transcript length: 3,178 bps, Translation length: 664 residues

MANE

This MANE Select transcript contains ENSP00000357283 and matches to NM_170707.4 and NP_733821.1

Uniprot

This transcript corresponds to the following Uniprot identifiers: P02545

CCDS

This transcript is a member of the Human CCDS set: CCDS1129

Transcript Support Level (TSL)

TSL:1

Version

ENST00000368300.9

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.