Transcript: ENST00000411769.1 CRKL-202

Description

CRK like proto-oncogene, adaptor protein [Source:HGNC Symbol;Acc:HGNC:2363]

Location

Chromosome 22: 20,917,434-20,953,747 forward strand.

About this transcript

This transcript has 4 exons, is annotated with 7 domains and features, is associated with 19948 variant alleles and maps to 364 oligo probes.

Gene

This transcript is a product of gene ENSG00000099942.13 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq Match	Flags
ENST00000354336.8	CRKL-201	5342	303aa	ENSP00000346300.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS13785	P46109	NM_005207.4	The Matched Annotation from NCBI and EMBL-EBI is a collaboration between Ensembl/GENCODE and RefSeq. The MANE Select is a default transcript per human gene that is representative of biology, well-supported, expressed and highly-conserved. This transcript set matches GRCh38 and is 100% identical between RefSeq and Ensembl/GENCODE for 5' UTR, CDS, splicing and 3'UTR.MANE Select, A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENST00000411769.1	CRKL-202	2037	303aa	ENSP00000396646.1	Nonsense mediated decay	CCDS13785	P46109	-	TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,

Summary

Statistics

Exons: 4, Coding exons: 3, Transcript length: 2,037 bps, Translation length: 303 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P46109

CCDS

This transcript is a member of the Human CCDS set: CCDS13785

Transcript Support Level (TSL)

TSL:1

Version

ENST00000411769.1

Type

Nonsense mediated decay

Annotation Method

Manual annotation (determined on a case-by-case basis) from the Havana project.

Transcript: ENST00000411769.1 CRKL-202

Summary

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Transcript: ENST00000411769.1 CRKL-202

Summary

About Us

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